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Unlock Order

If an upgrade is missing, the answer is usually one of three things: a prestige upgrade, enough workers in the right building, or a prerequisite tier in another upgrade chain.

UnlockRequirementsWhat It Opens
ManufactorumManufactorum prestige and The Great Forge acquired. It is then bought from Khazad Greathold.Bulldozers, Gyrocopters, machine hauling, machine defense, and anti-rock support.
BulldozerManufactorum placed. First Bulldozer costs 700 gold, 4 mithril, and 2 dwarves before scaling.Heavy ore collection, runner protection, and later machine upgrades.
CyberdwarfCyberdwarf prestige and more than 9 Scientists.Gorilla Arms, Rhino Legs, and the Cyberdwarf chain that leads into C.L.U.S.T.E.R.P.I.C.K.
C.L.U.S.T.E.R.P.I.C.K.C.L.U.S.T.E.R.P.I.C.K. prestige plus Cyberdwarf tier 2.Thrown pickaxes can split into 2-4 smaller half-damage pickaxes, with the chance increasing by Cyberdwarf tier.
AlchemyAlchemy prestige and more than 7 Scientists.Philosopher's Stone path and Alchemy Research scaling.
Ritual PowerRitual Power prestige and more than 2 Runesmiths. Tiers cost 666/3333/6666 gold and 1/2/3 souls.Unlocks ritual/enchant options and boosts specific rituals.
Flamelord's WrathFlamelords prestige plus the hidden requirement shown by the upgrade path: at least 6 Flamers and 5 Runesmiths.Troubleshooting target for fire builds. If it still does not appear, keep progressing through the confirmed fire, bomb, cannon, science, or machine lines.
SymptomCheck
The upgrade is not visible at all.Buy the related prestige upgrade first, then restart the run if the game only refreshes requirements after a prestige.
The upgrade is visible but blocked.Count the workers named by the icon requirement. Many advanced upgrades need Scientists or Runesmiths, not only the main unit.
The building is missing from Khazad Greathold.Check whether it is a prestige-gated building. Manufactorum is the common example.
The cost looks absurd or the button never becomes practical.Treat it as a chain that is not ready in your run. Put the gold into the current carry: Miner/Demodwarf damage if mountains are slow, Runners/Maw if ore is piling up, or Spelunker/Forge if mithril and artifacts are blocking you.
The unlock depends on another upgrade tier.Open the linked building page and follow the tier chain, especially Cyberdwarf, Mithril Forging, and Ritual Power.
PhaseUnlock Target
First stable runsRunners, Demodwarves, dens, and early PP.
Mithril starts blockingSpelunker's Guild, The Great Forge, Mithril Divining, and Rune of Fortune.
Mid-game utilityGrand Laboratory, Scientists, Manufactorum prestige, and machine hauling.
Late-game chainsCyberdwarf, C.L.U.S.T.E.R.P.I.C.K., Alchemy, Ritual Power, and special artifact gates.