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Best Prestige Upgrades

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Prestige is best spent on the problem that keeps coming back after resets. Early PP should shorten the opening loop; later PP should improve den rewards, mithril, gates, and ascension scaling.

QuestionAnswer
First useful targetPrestige around 14-15 PP if the run is slowing down. That lets you spend 12 PP to open Tier 2 and still buy one Tier 2 upgrade.
First buySwift Start if ore collection is slow; Ancestor's Picks if mountain damage is slow.
If you are stuckSpend PP on the bottleneck that repeats every run. Do not buy a weapon prestige for a weapon line you are not actually using.
When to pivotOnce basic clears are stable, move PP toward den rewards, mithril-luck, artifact carryover, route unlocks, and special gate support.
PhaseBest BuysPayoff
First 1-6 PPSwift Start first if ore collection is slow; Ancestor's Picks first if mountains are slow; Marching Orders once runner travel time is the repeated bottleneck.Do not spend just because a button is cheap. Pick the upgrade that fixes the first five minutes of the next run.
Early stabilityFleet-Footed And Rock-Hard · Orequake Finger · Heirloom InheritanceUseful when basic runs still need help surviving hazards, clearing ore, or starting with a useful artifact.
Dens and artifactsFated Finds · Undermined Foundations · Vault of KingsTake these when den clears are reliable enough that better den rewards and artifact carryover change the next run.
MithrilGreyglitter Leylines · Holy Pickaxe · Ascended Mithril CacheThese help when mithril is the currency bottleneck, either through luck, holy pickaxe procs, or ascension-starting mithril.
Damage specializationPowder Keg Lineage · Ballista Lore · Infernal Fortune · Deep PenetrationPick the line that matches your actual build. These are strongest when they support the damage branch you are already funding.
Gate and ascension prepKey Master · Ascetic Rites · Yeeti Arms · C.L.U.S.T.E.R.P.I.C.K.These matter when the goal shifts from clearing another normal mountain to special gates, rituals, and deeper permanent scaling.
HabitBetter Read
Buying every cheap permanent upgrade immediately.Cheap is only good if it changes the next run. A cheap bonus to the wrong system can wait.
Taking a weapon prestige for a weapon you are not using.Weapon prestige should follow your active damage branch.
Waiting too long on den/artifact prestige.If dens are already dying, guaranteed artifact and lower-den-HP effects can snowball quickly.
Ignoring start-of-run upgrades.Starting with runners, artifacts, mithril, or soul can remove dead time from every future run.
PrestigeRoute Change
ManufactorumAdds the machine route: Bulldozers, Gyrocopters, anti-rock support, and heavy hauling.
CyberdwarfOpens the Cyberdwarf chain in the Grand Laboratory, including runner cyber upgrades and C.L.U.S.T.E.R.P.I.C.K. setup.
C.L.U.S.T.E.R.P.I.C.K.Turns Miners into a late pickaxe-splitting branch after Cyberdwarf tier 2.
AlchemyOpens the Grand Laboratory route toward Philosopher's Stone, one of the Great World Spire artifacts.
Ritual PowerOpens Ritual Power tiers and the rituals that scale from those tiers.